The results in Table 2 supported Hypothesis 1 in that both Baseline SRE5-LR and impulsivity predicted a higher number of alcohol problems 4-years later. This finding is consistent with prior studies by our group (e.g., Schuckit and Smith, 2006; Schuckit et al., 2010, 2011), and was an important first step for evaluating Hypotheses 2–4. The documentation that many key variables correlated significantly with each other supports the importance of using SEM to test how these characteristics related over time when considered in the same prospective model.