Chunk #62 — Results — Haplotype accuracy in extended pedigrees — duoHMM corrected haplotypes

Source

A general approach for haplotype phasing across the full spectrum of relatedness.

Embedded

yes

Text

Table 2 shows the mean SE rate after applying haplotype corrections. The corrections lead to a consistent but small improvement for the SHAPEIT2 haplotypes, the largest improvement being a 0.009% decrease in SE for the CARL cohort. These results further highlight the very high quality haplotype estimates that SHAPEIT2 produces despite the fact it is ignoring all explicit pedigree information.