Six sites participating in the Collaborative Study on the Genetics of Alcoholism (COGA) (Begleiter et al., 1995; Foroud et al., 2000) recruited alcohol dependent probands from inpatient and outpatient facilities. The probands and their family members were administered a poly-diagnostic interview, the Semi-Structured Assessment for the Genetics of Alcoholism (SSAGA) (Bucholz et al., 1994; Hesselbrock et al., 1999). Individuals 17 years of age or younger were administered an adolescent version of the SSAGA. Institutional review boards at all sites approved the study.