LESS and AUDIT scores for those individuals with relatively low VS activity and high amygdala reactivity (parameter estimate=0.1468, SE: 0.0621, 95% CI: 0.0423–0.2885), but not for those with the opposite neural risk phenotype (parameter estimate=0.1187, SE: 0.0694, 95% CI: −0.0019–0.2763, Figure 4a). Self-reported hedonic responsiveness levels (MASQ AD scale) did not mediate the relationship between LESS and AUDIT scores at any level of VS activity or amygdala reactivity, possibly due to their lack of an association with recent stress in the current sample (b=−0.0118, SE: 0.0346, p=0.73).
