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Chunk #21 — Methods — Analytic Strategy

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Glucocorticoid Receptor (NR3C1) Gene Polymorphism Moderate Intervention Effects on the Developmental Trajectory of African-American Adolescent Alcohol Abuse.
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one year increase. An unconditional latent growth curve model without any covariate or predictor was first fitted using all participants to establish the most parsimonious growth model. Preliminary analyses revealed a small and significant quadratic slope, as well as a non-significant variance for the quadratic slope. Therefore, the variance for the quadratic slope was fixed at zero in all subsequent analyses. Next, ethnicity (1 = “AAs”, 0 = “EAs”), intervention status (1 = “intervention”, 0 = “control”), and covariates (gender, severity-of-risk screen score, age, cohort, and site) were included in the latent growth curve model to predict the intercept and linear slope.