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Chunk #1 — 1. Introduction

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Early auditory gamma-band responses in patients at clinical high risk for schizophrenia.
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Patients with schizophrenia have been shown to have abnormal electroencephalographic (EEG) gamma-band responses (GBRs) associated with sensory (Gallinat et al., 2004; Haig et al., 2000b; Hall et al., 2011a; Hall et al., 2011b; Kwon et al., 1999; Leicht et al., 2010b; Light et al., 2006; Roach and Mathalon, 2008; Spencer et al., 2008a), perceptual (Spencer et al., 2003), attentional (Haig et al., 2000a; Symond et al., 2005), and cognitive control (Cho et al., 2006) processes. We and others have recently reported decreased early gamma activity in response to auditory stimuli in patients with schizophrenia, as reflected by evoked power (Hall et al., 2011a; Hall et al., 2011b; Leicht et al., 2010b) and phase-locking factor (Hall et al., 2011b; Leicht et al., 2010b; Roach and Mathalon, 2008; Roach, this issue). In auditory oddball paradigms, schizophrenia has been associated with an abnormal reduction of GBRs to target (Haig et al., 2000b; Symond et al., 2005) and non-target (Haig et al., 2000b; Hall et al., 2011b; Roach and Mathalon, 2008) auditory tones, suggesting that the early-evoked GBRs to auditory stimuli are either compromised