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Chunk #29 — Discussion — Specific, Cognitive-Control-Related Functional Connectivity Deficits in Schizophrenia

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General and specific functional connectivity disturbances in first-episode schizophrenia during cognitive control performance.
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results accord with this prediction, because healthy individuals who found B trials more difficult, as reflected by relatively slower RTs, showed greater cingulofrontal connectivity during these trials. This association between connectivity and behavior was not present in the patient group, suggesting a breakdown of conflict monitoring and a relative failure to implement cognitive control, evidenced by patients’ significantly lower accuracy rates for BX trials. Together these data suggest that patients did not appropriately alter frontoparietal functional connectivity in response to increased cognitive control demands, resulting in a decoupling of network dynamics from task performance and a relative failure to implement control processes.