Of the 2,583 non-Hispanic European American samples from SAGE, 95 failed to pass quality control for CNV analysis, leaving 1,140 cases and 1,348 controls. The mean age among subjects with alcohol dependence was 38.2 [SD=10.0], and for controls was 39.0 [SD=9.5]. Sixty percent of the cases and 29.2% of the controls were male. As shown in Table 1, cases were more likely than controls to be dependent on nicotine and illicit drugs, including nicotine, cocaine, and marijuana. They were also more likely to meet criteria for a lifetime history of conduct disorder and major depression.
