2012). Furthermore, these analyses were performed in exclusively European ancestries, and as more diverse non-European samples and trans-ancestry GWAS become available, this is likely to improve TWAS and finemapping studies (Aguet et al., 2017; Pai et al., 2012; Veturi & Ritchie, 2018; Watson et al., 2019). Finally, the existing AN GWAS has predominately female composition which somewhat restricts the identification of sex specific causal risk/protective factors.
