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Chunk #6 — Results

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Extremely low-coverage sequencing and imputation increases power for genome-wide association studies.
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statistics obtained using extremely low-coverage sequencing did not exhibit the 9% drop that might have been expected given r2=0.91 imputation accuracy at these SNPs (ratio between the average −log 10 p-values at imputed versus typed data of 1.04), but this can be explained by statistical fluctuation (Table 1 and Supplementary Note).