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Chunk #12 — Process of Phenotype Harmonization — Identifying common phenotypes

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Phenotype harmonization and cross-study collaboration in GWAS consortia: the GENEVA experience.
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Phenotype harmonization starts with an inventory of phenotypes that investigators are interested in pursuing during cross-study analyses. For consortia involving only a few studies, or for consortia in which all studies have a common interest (e.g. stroke), this may only require a review of data collected by different studies and discussion among investigators. For collaborations such as GENEVA that incorporate studies of various designs and diverse outcomes of interest, a more extensive (formal survey) process is required.