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Chunk #6 — 1. Introduction

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Differential effects of ethanol in the nucleus accumbens shell of alcohol-preferring (P), alcohol-non-preferring (NP) and Wistar rats: a proteomics study.
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include W rats for comparison purposes to help interpret differences between P and NP rats as being mainly due to unique responses to ethanol in the P line, or unique responses to ethanol in the NP line. The hypothesis to be tested is that ethanol will differentially alter the levels of proteins involved in synaptic function in the ACB-shell between P and NP rats.