The surrogate phenotypes were specified in a sample set of 865 individuals primarily from three disparate continental populations, European (254 subjects), East Asia (283 subjects) and Africa (as represented by 328 African American subjects). In addition, the phenotype defined by SLC24A5 was examined in 1847 African American subjects. For each of the phenotypes examined, both putative true positives (SNPs located close to the chromosomal position of the modeled genotype) and false positives, unlinked SNPs were found with strong association (p <0.01 after Bonferroni correction) (Fig. 3 and Supplementary Table S5).
