This finding, however, parallels the results from a previous analysis of this sample where no influence of alcohol dependence was reported on these characteristics of bipolar disorder [16]. Additional findings such as the number of affective symptoms at baseline interview were most severe in Group 4 and measures of social functioning (GAF) which were lowest in both bipolar I and II subjects with CUD, may reflect a more severe impairment and more mood disorder symptoms in comorbid BD and CUD individuals.
