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Chunk #51 — STAR* METHODS — QUANTIFICATION AND STATISTICAL ANALYSIS — Factor analysis and genomic SEM

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Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders.
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compulsive and early onset factors (rg = < .01, SE = .07). A model that included additional negative cross-loadings provided similar fit to the data and highly similar correlations across the genetic factors. Given this consistency in results, the correlated factors model with SNP effects only included positive loadings.