We simulated summarized level data for 185 genetic variants indexed by j=1,2,…,J for 3 risk factors (X 1, X 2, X 3) and an outcome Y from the following data‐generating model: (14)βX1jβX2jβX3j∼N30.080.03−0.05,σ12ρ12σ1σ2ρ13σ1σ3ρ12σ1σ2σ22ρ23σ2σ3ρ13σ1σ3ρ23σ2σ3σ32βYj=αj′+θ1|βX1j|+θ2βX2j+θ3βX3j+ϵjϵj∼N(0,1)αj′∼N(μ,0.004).
