Chunk #11 — Results

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Tobacco smoking is associated with methylation of genes related to coronary artery disease.

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for all identified CpG sites stratified by the three smoking categories can be found in Additional file 2: Figure S1.Table 4Characteristics of significant CpG sitesAverage beta-values (SD)CpG siteGenePositiona PlacementCurrent smokersFormer smokersNever smokerscg24908166TERT5:1,268,800Body0.893 (0.031)0.900 (0.029)0.908 (0.024)cg12324353TERT5:1,269,197Body0.846 (0.027)0.851 (0.027)0.855 (0.024)cg03725309SARS1:109,757,585Body0.292 (0.057)0.297 (0.060)0.311 (0.063)cg00980784GNGT217:47,287,577TSS15000.331 (0.048)0.340 (0.048)0.341 (0.048)cg13916835SMG617:2,025,181Body0.796 (0.049)0.812 (0.047)0.822 (0.039)cg09469355SKI1:2,161,886Body0.500 (0.041)0.516 (0.045)0.520 (0.040)cg05603985SKI1:2,161,049First exon0.347 (0.037)0.362 (0.038)0.364 (0.037)cg04324276TOM1L217:17,817,462Body0.502 (0.047)0.502 (0.046)0.507 (0.047)cg25468516SIPA111:65,408,0285′UTR0.215 (0.048)0.218 (0.051)0.226 (0.054)cg22907952MRAS3:138,121,2873′UTR0.806 (0.033)0.809 (0.034)0.812 (0.030)cg15474579CDKN1A6:36,753,790Body0.706 (0.058)0.718 (0.052)0.726 (0.047)cg20496896LRRC23:46,579,532Body0.728 (0.056)0.727 (0.055)0.712 (0.056)cg09397246FES15:91,427,361TSS15000.296 (0.066)0.285 (0.065)0.286 (0.062)cg26405020FES15:91,427,363TSS15000.464 (0.057)0.459 (0.059)0.457 (0.055)cg18236066RPH3A12:113,293,823Body0.702 (0.040)0.709 (0.038)0.713 (0.041)TSS1500, 1500 base pairs for transcription start sites aBased on genome build 37