The task scan used the Hariri faces/shapes “emotion” task21, 73, as implemented in the HCP22,, but with shorter overall duration and hence fewer total stimulus block repeats. The participants are presented with blocks of face or shape trials and asked to decide which of two faces (or shapes) presented on the bottom of the screen match the face (or shape) at the top of the screen. The faces have either angry or fearful expressions. The ePrime stimulus script is available for download (http://biobank.ctsu.ox.ac.uk/crystal/refer.cgi?id=1462). Task-induced activation is modeled with FEAT, including auto-correlation correction74, using 5 activation contrasts. Of these, the three activation contrasts of most interest (shapes, faces and faces>shapes) are used to generate output measures, including two IDPs for the faces-shapes task (one including all voxels above a group-level fixed-effects Z>120, and one including only the amygdala regions above threshold). IDPs corresponding to both percent signal change and statistical significance (Z statistics) are generated.
