ALSPAC is a longitudinal, population-based birth cohort study that began with 14,501 pregnant women resident in Avon, England in 1991 and 1992 [33]. Data were regularly collected via self-completion questionnaires sent to the mothers since their enrollment during pregnancy and through the child’s early years. In addition, a subset of approximately 8,000 children from the original offspring have been followed since the age of seven using hands-on assessments. Ethical approval for the study was obtained from the ALSPAC Law and Ethics Committee and the Local Research Ethics Committees as described on the ALSPAC website: http://www.alspac.bris.ac.uk. The current analyses are based on the subgroup of 688 13-to-14-year-old offspring who were drinkers and who were studied in person in the ongoing age 13/14-year evaluation (also known as a “clinic”).
