The THINC-it tool has been developed in response to the need for a brief screening instrument for detecting cognitive deficits in patients with depression. It was designed to screen – not to diagnose – for objectively assessed cognitive function in depression by employing a variety of well-established cognitive tests (93). The tool contains tests of digit coding, choice reaction time, the one-back memory paradigm, and various versions of the Trail Making Test Part B. In addition, measure of subjectively reported cognitive deficits – Perceived Deficit Questionnaire (PDQ) – has been added to the THINC-it assessment tool (94, 95).