To address these challenges, the National Cancer Institute (NCI) sponsored a Gene-Environment Think Tank, held on January 10th–11th, 2012. The goal of the meeting was to facilitate discussion on GxE interaction studies in cancer epidemiology, with a focus on current progress, and recommendations for future research [http://epi.grants.cancer.gov/workshops/thinktank/]. Presentations covered a broad spectrum of topics, including: rationale for GxE studies; state of the science; optimal study designs; emerging approaches for analytic methods; challenges and opportunities in measurement of the environment; and clinical and public health implications.
