Overall, it appears that while girls and boys may be facing similar vulnerabilities for problems with alcohol, boys begin to carry more risk as they move towards young adulthood. This review does not suggest that clinical research and treatment should then focus primarily on the escalation of use in boys, but instead, calls for more gender-sensitive studies in order to provide a clearer picture on what factors are most salient for both sexes. This information can then greatly inform intervention strategies for all youth.