The inclusion of individuals from non-European ancestries in genetic analyses is crucial for health-care equity and genetic discovery41. Therefore, we performed additional collapsing analyses for each major non-European ancestral group (that is, South Asian (n = 5,714), African (n = 4,744) and East Asian (n = 1,475)). We limited each PheWAS to binary traits with at least five cases in the population and quantitative traits with at least five qualifying variants carriers (Supplementary Table 1).
