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Chunk #16 — Methods — Genetic Analyses

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Association of single nucleotide polymorphisms in a glutamate receptor gene (GRM8) with theta power of event-related oscillations and alcohol dependence.
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In this study, a quantitative trait, theta band (4–5 Hz) amplitude of EROs, and a dichotomous variable (i.e., alcohol dependent vs. not) were the phenotypes tested. Age and gender were treated as covariates. False discovery rate, FDR (Benjamini and Hochberg 1995; Storey and Tibshirani 2003), was calculated to correct for multiple comparisons with the method developed by Storey (2003).