The negative life events model is presented in Fig. 4 and Table 8 in the appendix. Depression and physical aggression included scalars to account for variance differences between the sexes. All genetic variance in negative life events was accounted for by its association with the other phenotypes in the model. The residual genetic variance estimate in the Cholesky decomposition was 0.00 (95 % confidence intervals: 0.00, 0.13). The genetic correlation between negative life events and oppositionality was 0.94 (0.83, 1.00), with delinquency it was 0.99 (0.73, 1.00), with physical aggression it was 0.68 (0.36, 0.96), with depression it was 0.57 (0.26, 0.97), and with anxiety it was.32 (−0.07, 0.83). Table 8Negative life events: correlated factors solution showing the aetiological overlap between negative life events and 5 behavioural phenotypesACE1.2.3.4.5.6.1.2.3.4.5.6.1.2.3.4.5.6.1. Oppositionality0.36(0.20, 0.48)0.06(0.00, 0.18)0.58(0.50, 0.66)2. Delinquency0.94(0.84, 1.00)0.50(0.35, 0.59)−0.05(−0.80, 0.71)0.09(0.03, 0.21)0.39(0.30, 0.47)0.41(0.35, 0.48)3. Physical aggressiona 0.77(0.67, 0.96)0.69(0.57, 0.99)0.48(0.38, 0.55)0.52(−1.00, 1.00)0.62(−1.00, 1.00)0.02(0.00, 0.07)0.33(0.24, 0.41)0.32(23, 0.41)0.51(0.43, 0.59)4. Depressiona 0.66(0.48, 0.89)0.59(0.38, 0.99)0.44(0.19, 0.74)0.32(0.15, 0.46)0.35(−0.50, 0.76)0.46(−0.43, 0.96)0.32(−0.60, 1.00)0.14(0.04, 0.28)0.34(0.25, 0.41)0.17(0.06, 0.27)0.10(−0.01, 0.20)0.54(0.47, 0.62)5. Anxiety0.31(0.11, 0.52)0.34(0.11, 0.61)0.19(−0.04, 0.48)0.83(0.63, 0.95)0.38(0.19, 55)0.48(−0.02, 0.89)−0.10(−0.90, 0.59)−0.07(−0.81, 0.75)0.66(0.03, 0.90)0.16(0.02, 0.32)0.25(0.16, 0.34)0.11(0.01, 0.22)0.04(−0.07, 0.14)0.49(0.41, 0.56)0.46(0.40,