sampling variances of the respective SNP-genotype covariances.11,44 A final block of the VSFull matrix represents the sampling covariance of the SNP-genotype covariances with the genetic variances and genetic covariances. These are fixed to 0, as sampling variation of the SNP-genotype covariance is expected to be independent of the test statistics of all LD blocks except the one it occupies. Because the sampling variance of the heritabilities and genetic correlations derive from sampling variability in the test statistics within all of the LD blocks, their sampling covariances with a single SNP effect is expected to approach 0. In sum, the VSFull matrix can be written in compact form as: VSFull=[VSSNP0VSLDSC]
