these genes. For this gene subset, we found many more SNPs having small q values, including 27 SNPs with q-value < 0.4 and 39 SNPs with q-value < 0.5, than those in other gene sets (e.g., gene subset with score ≥ 1.5 or any scored, Table 4). Although this q-value analysis was not perfect (e.g., we did not find a steady decrease of q-value by increasing gene score, Table 4), it suggests that multi-species gene ranking by optimal weighting matrix might be effective for prioritizing candidate genes for complex traits.
