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Chunk #87 — Discussion — Extensions

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A flexible and accurate genotype imputation method for the next generation of genome-wide association studies.
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IMPUTE v2 is already fast enough to use in large association studies, but we also have plans to make it faster. We believe that the software can gain some speed simply by optimizing the code, but we also have plans to implement an analytical speed-up for the HMM forward-backward calculations [22] that may further decrease running times by a factor of five or so.