Chunk #8 — Results/Discussion

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Tissue-specific genetic control of splicing: implications for the study of complex traits.

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For all high confidence associations identified, we evaluated how often the expression effects of SNPs were observed in the other tissue, and found that 74% of eQTLs and 51% of sQTLs appeared to act exclusively in one tissue or the other. These data clearly indicate a significant role of tissue-specific genetic regulation.