It can be surprisingly difficult to retrace the computational steps performed in a genomics research project. One of the goals of Bioconductor is to help scientists report their analyses in a way that allows exact recreation by a third party of all computations that transform the input data into the results, including figures, tables and numbers [9]. The project's contributions comprise an emphasis on literate programming vignettes, the BiocStyle and ReportingTools packages, the assembly of experiment data and annotation packages, and the archiving and availability of all previously released packages. A number of developments in the wider R community, including the knitr and rmarkdown packages and the integrated development environment RStudio, make it easy to author attractive vignettes. In addition to the traditional delivery format as a PDF file, the newer generation of tools allow use of HTML5 facilities for interactive visualization, including ‘drill-down’ to expand the view on a specific detail, faceted filtering and comprehensive hyperlinking. Full remote reproducibility remains a challenging problem, in particular for computations that require large computing resources or access data through infrastructure that is
