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Chunk #42 — Background — Description of clinical characteristics of KPD and how the family data were collected and classified

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Construction of the model for the Genetic Analysis Workshop 14 simulated data: genotype-phenotype relationships, gene interaction, linkage, association, disequilibrium, and ascertainment effects for a complex phenotype.
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6. A strong aversion to travel by foot (i.e., walking). Patients will use their vehicles (large, gasoline-consuming behemoths are preferred by KPD suffers) to travel distances in which walking would take less time than driving; thus, speed of travel plays no rational role in the manifestation of this phenotype. Also, a common delusion among patients is that travel to any location always takes twenty minutes. (Note: This tendency was reported to be characteristic as early as the 18th century and is thus one of the earliest-noted symptoms of KPD.)