larger time-series variance of PAC in pressing and slow tapping tasks compared with the resting state of controls may hint at the possibility that PAC may be modulated at particular movement events. However, direct comparisons of CoV between patients and controls did not reveal any significant differences in the tasks (Fig. 4B), even though we noticed different variability of PAC between patients and controls in Fig. 4A This may be because CoV measurement can only evaluate the general variability of PAC over time, and lost power to detect the changes at specific transition times. Therefore, we subsequently investigated the modulation of movement-related PAC across transitions between different movement states in the pressing and slow tapping tasks (“dynamic PAC”).
