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Chunk #4 — Introduction

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Associations of OPRM1 A118G and alcohol sensitivity with intravenous alcohol self-administration in young adults.
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between operant responses and aBAC increases. Coupled with a relatively rapid decline in aBAC (due to immediate blood-to-tissue distribution), this feature allows relatively better control over self-imposed aBAC compared to oral methods (Zimmermann et al., 2008). Additionally, the absence of conditioned sensory cues is presumed to isolate perceived alcohol effects (relative to desired effects) as the main determinant of self-administration (Zimmermann et al., 2008).