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Chunk #25 — Methods — Ethics statement

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Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations.
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We here performed secondary data analysis on deidentified data only (exempt research). Access to TOPMed data was approved by the University of North Carolina at Chapel Hill Institutional Review board (study 16–2213). All individual studies included in TOPMed were approved by relevant local ethical review boards.