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Chunk #39 — Methods — Surface-based MRI analysis

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Resting state fMRI connectivity is sensitive to laminar connectional architecture in the human brain.
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Cortical surface reconstruction of the cerebral cortex from magnetic resonance images is a major step in the quantitative analysis of the human brain structure. Cortical reconstruction approaches with Freesurfer are optimized for standard resolution (~ 1 mm) data. However, in this work, we applied Lüsebrink’s method to preprocess high-resolution anatomical MRI data with our original 0.6 mm isotropic resolution using FreeSurfer 6 beta version [82]. The white/gray and gray/CSF interfaces, as well as cortical thickness maps were automatically generated with FreeSurfer (Fig. 1). The surfaces generated by Freesurfer are represented in the form of triangular meshes, and each triangle has three vertices. In addition, a set of 3D coordinates of these surfaces gives the position of the vertices.