developing psychological disorders in childhood or later in life. Investigation of the epigenetic mechanisms which may underlie a suite of psychological disorders, including but not limited to post-traumatic stress disorder (PTSD), depression, schizophrenia, and ADHD, may provide researchers with a greater understanding of the potential epigenetic nature of these disorders while also providing novel therapeutic and pharmacokinetic targets for treatment. Both candidate and genome-wide association studies should be employed to investigate how maternal cigarette smoking during pregnancy might influence risk for neuropsychiatric disease through epigenetic mechanisms.