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Chunk #15 — Results — Gene set enrichment analysis

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Integrating mRNA and miRNA Weighted Gene Co-Expression Networks with eQTLs in the Nucleus Accumbens of Subjects with Alcohol Dependence.
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Using the default parameters in GSEA, we identified 364 a priori gene sets significantly enriched (FDR≤ 0.10) within the six MM ranked gene lists. Of these, 117 a priori gene sets were enriched in multiple (≥2) modules. Interestingly, no a priori gene sets were shared between glial cell-associated modules, M green, M grey60, M pink and M salmon, and the neuron-associated modules, M turquoise and M yellow.