15q15.2. Two other SNPs associated with lung cancer risk at P < 10−5 also map to 15q15.2 (rs504417 and rs11853991, 41,341,518bp and 41,344,841bp respectively) and are in strong LD with rs748404 (respective r2 values for: rs748404–rs504417, rs748404–rs504417 are 0.65 and 0.68 based on HapMap CEU, and 0.59 and 0.61 based on UK-GWA Phase 2 controls) rs748404 maps 3’ to Transglutaminase 5 (TGM5), with rs504417 and rs11853991 mapping to intron 1 of this gene.
