SNPs in the GWAS, this would have shown in the repeat analysis results. In spite of intensive QC, spurious associations may occur. We considered the top variant (rs6462756, near SDK1 gene) of the analysis of males and females combined as a plausible false positive, as it was the only signal from that genomic region (7p22.2), where the SNP density was not particularly sparse, rather to the contrary, relatively dense (35 SNPs per 100 kb, compared with chr 7p average 21 SNPs per 100 kb and the nearby 500 kb average 25 SNPs per 100 kb), and thus, it was not selected to the regenotyping nor to the replication study.
