This review suggests that exercise may be an acceptable and feasible alternative or adjunctive intervention to enhance mood, functioning, and comorbid conditions for individuals with MDD or bipolar disorder. The literature suggests that exercise is beneficial as an adjunctive intervention for depression; however, few rigorous studies have been conducted with exercise as an adjunct to treatment as usual, especially for bipolar disorder. For this reason, we included all forms and intensity of exercise in this review, but it is also important to note that not all exercise has the same positive effect. For example, aerobic exercise is typically considered more effective for improving cardiovascular health, increasing well-being, and managing chronic conditions such as diabetes mellitus [34, 129], while anaerobic exercise has particular benefit for improving respiratory fitness and reducing oxidative stress, and fatigue [32]. Further research is needed to determine the most effective type, duration, and intensity of exercise for individuals with mood disorders, but it is likely that a balance between aerobic and anaerobic exercises would provide the most health benefits. For example, given that mood disorders are characterized