Sexual abuse increased the hazard of cannabis initiation for EA women across all risk periods [HR = 1.19, 95%CI: (1.03–1.38)] and AA women prior to the age of 15 [HR = 2.20, 95%CI: (1.11–4.39)]. Witnessing another person being killed or injured [HR = 1.36, 95%CI: (1.02–1.81)] and experiencing an accident [HR = 1.68, 95%CI: (1.27–2.22)] were associated with increased initiation of cannabis among AA women only. In EA women only, physical abuse [HR = 1.21, 95%CI: (1.07–1.37)] and MDD [HR = 1.43, 95%CI: (1.19–1.71)] also increased the risk for cannabis initiation. For AA women, the increased hazard conferred by alcohol use [HR = 2.79, 95%CI: (2.07–3.75)] and tobacco use [HR = 2.69, 95%CI: (2.04–3.54)] for cannabis initiation was consistent across all risk periods. The largest magnitude risk for cannabis initiation was conferred by alcohol use [HR = 4.74, 95%CI: (3.77–5.96)] and tobacco use [HR = 6.69, 95%CI: (5.18–8.64)] during adolescent years (ages 15–18) in EA women(Table 3 and Fig. 1). Posttraumatic stress disorder did not significantly increase the hazard for cannabis initiation in EA or AA women.
