be due to a number of factors, not the least of which is procedural differences between the studies, but, in addition, proteins may be synthesized in other regions and transported to the ACB. Another possibility is that there is temporal discontinuity between changes in the expression levels of mRNA and protein, such that protein levels may increase (or decrease) leading to their accumulation (or reduction) because of post-translational modifications and/or changes in chaperoning or trafficking.