Chunk #32 — Discussion

Source

Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use.

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Gene based tests identified a small number of associated genes, including an expected association with ADH1C and drinks per week. The other two associated genes, ARHGEF37 and HEATR5A, do not lend themselves to ready biological interpretations.