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Chunk #3 — 1. Introduction

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Evidence of allelic imbalance in the schizophrenia susceptibility gene ZNF804A in human dorsolateral prefrontal cortex.
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We investigated the role of ZNF804A plays in SZ and BD by: i) genotyping the rs1344706 and rs12476147 SNPs in a sample of 428 SZ, 385 BD, and 578 controls from an isolated population from Costa Rica (DeLisi et al., 2001; Morera et al., 2003); and ii) analyzing the rs1344706 allelic specific expression (ASE) in the postmortem dorsolateral prefrontal cortex (DLPFC).