Within this cohort, we identified 10 155 persons with OCD, 40 439 with anxiety disorders, 76 202 with depression, and 134 787 with substance use disorders. Persons who received a diagnosis of OCD (5935 females and 4220 males with a mean [SD] age of 29.1 [11.3] years) contributed a total of 54 937 person-years of observation. Of the 10 155 persons with OCD, 1810 (17.8%) received a comorbid diagnosis of an anxiety disorder, 2682 (26.4%) received a comorbid diagnosis of depression, and 1362 (13.4%) received a comorbid diagnosis of a substance use disorder. A total of 110 persons with OCD (1.1%) died during the follow-up period, including 82 persons (1.5%) with comorbid anxiety disorders, depression, or substance use disorders. Table 1 shows the details of the mortality rates for a priori selected covariates.