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Chunk #3 — Method — Procedures

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Polymorphisms of the mu-opioid receptor and dopamine D4 receptor genes and subjective responses to alcohol in the natural environment.
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At the end of the 5-day baseline period, one participant failed to meet the minimal EMA compliance criterion of responding to at least 50% of random prompts and was discontinued from the study. The placebo lead-in portion of the study started at week two and randomization to the medication portion at week three, as described elsewhere (Tidey et al., 2008). DNA collection was performed via buccal swabs using established procedures (Freeman et al., 1997; Lench et al., 1988).