Chunk #23 — Materials and Methods — Training and validation data sets for predicting height in Africans: UK Biobank and N'Diaye et al

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Multiethnic polygenic risk scores improve risk prediction in diverse populations.

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pair of relatives with relatedness greater than 20% (n=32). We performed a PCA analysis using EIGENSTRAT (Price et al., 2006) (see Web Resources) to identify and remove genetic outliers, but did not identify any outliers. We restricted our analysis to 232,182 SNPs present in the UK Biobank and N'Diaye et al. data sets after removing A/T and C/G SNPs to eliminate potential strand ambiguity.