As depicted in Figure 2 (a and b), the initial pairing of intraoral sucrose (CS1) and ethanol increased preference for the sandpaper-lined compartment (CS2). The ANOVA yielded a significant main effect of conditioning group for absolute and percent time spent on CS2: F(2, 68) = 5.58; p< 0.005 and F (2,68) = 4.12; p < 0.05, respectively. Post-hoc tests indicated that adolescents in the EP and LP paired groups spent significantly more time in the CS2 compartment than the unpaired condition (p < 0.05 and p < 0.005, respectively). Inspection of Fig. 2a also suggests that the conditioning effect is driven largely by the 2.0 g/kg group, but this was not confirmed statistically; no significant main effect nor significant interaction comprising ethanol dose was detected by the ANOVA.
