Results from the GWAS of moderate-to-severe COPD in the COPDGene non-Hispanic whites and African-Americans are shown in Tables S6 and S7. The analysis in the non-Hispanic whites confirmed three previously known (CHRNA3/5/IREB2, HHIP, and FAM13A) COPD susceptibility loci, but neither study alone identified novel loci achieving conventional genome-wide significance (P < 5•0×10−8, Table S7 and S8).