Chunk #45 — Materials and Methods — Assessment of Subjects’ Familial Adversity, Behavior Problems, Psychiatric Diagnoses and Criminal Records — Physical aggression and other behavior problems

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Differential DNA methylation regions in cytokine and transcription factor genomic loci associate with childhood physical aggression.

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In the course of the longitudinal studies, teachers annually rated the frequency of boys’ physical aggression, opposition, hyperactivity, inattention and anxiety from kindergarten to secondary school with the Social Behavior Questionnaire [96]. The physical aggression ratings were used to trace the developmental trajectories and create the CPA group and the control group (see [6] and [11] for details of the trajectory analyses).